Effect of acute hypoxia on the phospholipid composition of the cell, microsomal and mitochondrial membranes of rat brain and liver
Ternovoĭ, V.A.; Mikhaĭlov, I.V.; Iakovlev, V.M.
Voprosy Meditsinskoi Khimii 39(5): 50-52
1993
ISSN/ISBN: 0042-8809 PMID: 8279146 Document Number: 407017
Tissue-dependent alterations in composition of phospholipids, studied by means of thin-layer chromatography, were detected in plasma, microsomal and mitochondrial membranes of rat brain and liver tissues after influence of acute hypoxia in the altitude chamber at a "height" of 12,000 m 3-9 min. These alterations were maintained within 2 weeks after the acute hypoxia effect in all the membranes studied, while they were most distinct in plasma and mitochondrial membranes. In the group of hypoxia-stable rats the alterations in phospholipids were more pronounced as compared with the group of less stable animals.