Top Abstract Purchase Related
Home
>
Node
>
Subnode

Effect of estradiol on phosphoinositide composition of nuclear membranes of rat brain cells

Gevorkian, E.S.; Iavroian, Z.V.; Artsruni, I.G.; Akopian, N.R.; Demirkhanian, L.O.

Ukrainskii Biokhimicheskii Zhurnal 70(1): 48-52

1998

ISSN/ISBN: 0201-8470
PMID: 9848139
Document Number: 490307
The effect of estradiol on phospholipids and particularly on phosphoinositides of nuclear membranes of rat brain cells at different stages of hormone action was investigated. It was shown that hormone leads to the elevation of phospholipids total amount at the primary and early stages of its action (1 and 4 h after estradiol injection, correspondingly). The increase of content of almost all individual fractions of phospholipids as well as phosphatidylinositol (i.e. monophosphoinositide) was detected. It is remarkable that the monophosphoinositides elevation takes place mainly due to the decrease of di- and especially of triphosphoinositide. The ratio of triphosphoinositide/monophosphoinositide decreases more than twice. It was concluded that the ratio of triphosphoinositide to monophosphoinositide may be a peculiar indicator of the status of nuclear membranes for the functioning of triphosphoinositide regulatory system.

Document emailed within 1 workday
Secure & encrypted payments

Gevorkian, E.S.; Tadevosian, I.V. 1990: The effect of estradiol on the initiation of phosphoinositide catabolism in rat brain synaptic membranes Biokhimiia 55(8): 1381-1386
Gevorkian, E.S.; Tadevosian, I.V.; Iavroian, Z.V.; Gevorkian, G.A. 1986: Effect of hydrocortisone on the phospholipid composition and activity of various enzymes of phospholipid metabolism in the nuclear membranes of the rat liver Biokhimiia 51(10): 1630-1634
Ternovoĭ, V.A.; Mikhaĭlov, I.V.; Iakovlev, V.M. 1993: Effect of acute hypoxia on the phospholipid composition of the cell, microsomal and mitochondrial membranes of rat brain and liver Voprosy Meditsinskoi Khimii 39(5): 50-52
Tarakhovskiĭ, A.M.; Shliakhovenko, V.A.; Zhmareva, E.N.; Brodskaia, I.A.; Peskin, A.V. 1985: Formation of superoxide radicals by the nuclear membranes of human brain tumors Biulleten' Eksperimental'noi Biologii i Meditsiny 99(1): 88-90
Vincendon, G.; Morgan, I.G.; Gombos, G.; Breckenridge, W.C. 1972: Comparative study of the composition of the synaptic vesicles and synaptosomal plasma membranes of the rat brain Journal de Physiologie 65: Suppl. 1: 173a
Mineeva, E.N. 1990: The competitive relations of tamoxifen and estradiol at the level of the plasma membranes of the target cells Farmakologiia i Toksikologiia 53(6): 26-27
Grandi, G.; Piacenti, I.; Volpe, A.; Cagnacci, A. 2014: Modification of body composition and metabolism during oral contraceptives containing non-androgenic progestins in association with estradiol or ethinyl estradiol Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology 30(9): 676-680
Lippert, C.; Seeger, H.; Wallwiener, D.; Mueck, A.O. 2001: The effect of medroxyprogesterone acetate and norethisterone on the estradiol stimulated proliferation in MCF-7 cells: comparison of continuous combined versus sequential combined estradiol/progestin treatment European Journal of Gynaecological Oncology 22(5): 331-335
Manzoli, L.; Billi, A.M.; Faenza, I.; Matteucci, A.; Martelli, A.M.; Peruzzi, D.; Falconi, M.; Rhee, S.G.; Gilmour, R.S.; Cocco, L. 1999: Nuclear phospholipase C: a novel aspect of phosphoinositide signalling Anticancer Research 19(5a): 3753-3756
Volkov, V.I.; Velikanov, G.A. 1979: Study of water transport in the membranes of yeast cells by the impulse method of nuclear magnetic resonance Biofizika 24(1): 77-81
Shubochkin, A.I.; Sidorenkov, I.V.; Danilin, V.A. 1980: Effect of vibration and noise on the lipid composition of cell membranes Gigiena Truda i Professional'nye Zabolevaniya (4): 48-49
Gaziev, A.I.; Kutsyĭ, M.P. 1985: Reorganization of the protein composition of the nuclear matrix of hepatoma cells after inhibition of DNA synthesis with novobiocin Biokhimiia 50(12): 2010-2015
Digiorgio, V.M.; Cafagna, F.; Ruggiero, F.M. 1988: The effect of thyroid hormones on the lipid composition of rat plasma and erythrocyte membranes Bollettino della Societa Italiana di Biologia Sperimentale 64(11): 979-984
Akopov, S.B.; Bul'diaeva, T.V.; Kuz'mina, S.N.; Zbarskiĭ, I.B. 1985: Effect of hyperthermia on the polypeptide composition of the nuclear matrix of the rat liver Biokhimiia 50(7): 1127-1131
Narasimhan, T.R.; Safe, S.; Williams, H.J.; Scott, A.I. 1991: Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on 17 beta-estradiol-induced glucose metabolism in MCF-7 human breast cancer cells: 13C nuclear magnetic resonance spectroscopy studies Molecular Pharmacology 40(6): 1029-1035
Kagan, V.E.; Arkhipenko, I.V.; Kozlov, I.P. 1983: Modification of the enzyme system for Ca2+ transport in sarcoplasmic reticulum membranes during lipid peroxidation. Changes in the chemical composition and ultrastructural organization of the membranes Biokhimiia 48(1): 158-166
Gubskiĭ, I.I.; Afonina, G.B.; Briuzgina, T.S.; Kravchenko, E.I.; Radlovskaia, Z.T. 1989: The effect of levamisole on the functional activity and fatty acid composition of lymphocytes after the damage of cell membranes with tetrachloromethane Voprosy Meditsinskoi Khimii 35(2): 64-68
Hula, N.M.; Marhitych, V.M.; Klimashevs'kyĭ, V.M.; Horid'ko, T.M.; Artamonov, M.V.; Zhukov, O.D. 2005: Neuroprotective effect of N-acylethanolamines in chronic morphine dependence. II. Effect on the rat brain fatty acid composition Ukrains'kyi Biokhimichnyi Zhurnal 77(2): 112-117
Varga, S.V.; Reznikov, A.G. 1978: Estradiol-binding and estradiol-inhibiting capacity of the target organs in female rats with brain-disturbed sexual differentiation Fiziolohichnyi Zhurnal 24(1): 3-6
Khalili, K.; Rappaport, J.; Khoury, G. 1988: Nuclear factors in human brain cells bind specifically to the JCV regulatory region EMBO Journal 7(4): 1205-1210