Top Abstract Purchase Related
Home
>
Node
>
Subnode

The effect of estradiol on the initiation of phosphoinositide catabolism in rat brain synaptic membranes

Gevorkian, E.S.; Tadevosian, I.V.

Biokhimiia 55(8): 1381-1386

1990

ISSN/ISBN: 0320-9725
PMID: 1963087
Document Number: 351156
The in vivo effect of estradiol on phosphoinositide catabolism initiation provoked by K(+)-depolarization of rat brain synaptosomal membranes was studied. The decreased yield of diacylglyceride was revealed on the 5th sec of initiation. It was found that estradiol markedly increases the phospholipid content, particularly that of phosphatidylinositol, in synaptosomal membranes but causes a simultaneous decrease of the neutral lipid content. The activity of phosphatidylinositol-specific phospholipase C is significantly decreased thereby. It was concluded that the effect of the steroid hormone on the genome provides for a functional status of membrane structures which slightly impedes the processes mediated by phosphoinositides.

Document emailed within 1 workday
Secure & encrypted payments

Gevorkian, E.S.; Iavroian, Z.V.; Artsruni, I.G.; Akopian, N.R.; Demirkhanian, L.O. 1998: Effect of estradiol on phosphoinositide composition of nuclear membranes of rat brain cells Ukrainskii Biokhimicheskii Zhurnal 70(1): 48-52
Mule, S.J.; Casella, G.; Clouet, D.H. 1974: Localization of narcotic analgesics in synaptic membranes of rat brain Research Communications in Chemical Pathology and Pharmacology 9(1): 55-77
Aksentsev, S.L.; Okun', I.M.; Miliutin, A.A.; Beliaeva, E.I.; Konev, S.V. 1982: Comparative study of beta-adrenoreceptors of rat brain synaptic membranes Biofizika 27(1): 156-158
Vincendon, G.; Morgan, I.G.; Gombos, G.; Breckenridge, W.C. 1972: Comparative study of the composition of the synaptic vesicles and synaptosomal plasma membranes of the rat brain Journal de Physiologie 65: Suppl. 1: 173a
Johnson, P.S.; Michaelis, E.K. 1992: Characterization of organophosphate interactions at N-methyl-D-aspartate receptors in brain synaptic membranes Molecular Pharmacology 41(4): 750-756
Rozhanets, V.V.; Rusakov, D.I.; Val'dman, A.V. 1982: Affinity of various antidepressive agents to imipramine receptors of synaptic membranes in mouse brain Biulleten' Eksperimental'noi Biologii i Meditsiny 94(10): 42-43
Burbach, J.P.; Wang, X.; van Ittersum, M. 1982: Difference in susceptibility of arginine-vasopressin and oxytocin to aminopeptidase activity in brain synaptic membranes Biochemical and Biophysical Research Communications 108(3): 1165-1171
Cavallotti, C.; Iacobelli, S.; Amenta, F. 1975: Effect of some detergents on synaptic membranes Bollettino della Societa Italiana di Biologia Sperimentale 51(18): 1126-1132
Kryzhanovskiĭ, G.N.; Sandalov, I.G.; Rodina, V.I.; Rozhanets, V.V.; Glebov, R.N. 1977: Effect of tetanus toxin and colchicine on synaptic membranes of rat cerebral cortex Biulleten' Eksperimental'noi Biologii i Meditsiny 83(2): 139-142
Kuchmerovskaia, T.M.; Klimenko, A.P.; Parkhomets, P.K.; Donchenko, G.V. 1993: Effect of NAD on uptake and release of some mediators by synaptic vesicles of the rat's brain Ukrainskii Biokhimicheskii Zhurnal 65(3): 66-70
Naumov, I.I. 1976: Effect of narcotics on the enzymatic activity of neuronal and synaptic mitochondria of rat brain Farmakologiia i Toksikologiia 39(3): 268-271
Mokrushin, A.A.; Bagaeva, T.R.; Gerasimova, I.A.; Emel'ianov, N.A. 1988: Effect of hydrocortisone on synaptic transmission in surviving slices of the olfactory cortex from the rat brain Problemy Endokrinologii 34(6): 52-56
Dagani, F.; Gorini, A.; Polgatti, M.; Villa, R.F.; Benzi, G. 1983: Synaptic and non-synaptic mitochondria from rat cerebral cortex. Characterization and effect of pharmacological treatment on some enzyme activities related to energy transduction Il Farmaco; Edizione Scientifica 38(8): 584-594
Varga, S.V.; Reznikov, A.G. 1978: Estradiol-binding and estradiol-inhibiting capacity of the target organs in female rats with brain-disturbed sexual differentiation Fiziolohichnyi Zhurnal 24(1): 3-6
Samsonova, N.A.; Glebov, R.N. 1981: Status of active and passive cation transport through cerebral synaptic membranes during seizures Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 81(6): 921-929
Mazzanti, L.; Curatola, G.; Zolese, G.; Bertoli, E.; Lenaz, G. 1979: Molecular mechanism of general anesthesia: II. Spin label studies on synaptic membranes Bollettino della Societa Italiana di Biologia Sperimentale 55(6): 506-510
Balduini, W.; Murphy, S.D.; Costa, L.G. 1987: Developmental changes in muscarinic receptor-stimulated phosphoinositide metabolism in rat brain Journal of Pharmacology and Experimental Therapeutics 241(2): 421-427
Kropotov, I.D.; Pakhomov, S.V. 1984: Mathematical modeling of the mechanisms of signal processing by neuronal populations in the brain. II. the effect of synaptic plasticity on the properties of the neuronal network with local connections in the stationary mode Fiziologiia Cheloveka 10(3): 405-410
Keefe, D.L.; Michelson, D.S.; Lee, S.H.; Naftolin, F. 1991: Astrocytes within the hypothalamic arcuate nucleus contain estrogen-sensitive peroxidase, bind fluorescein-conjugated estradiol, and may mediate synaptic plasticity in the rat American Journal of Obstetrics and Gynecology 164(4): 959-966
Ternovoĭ, V.A.; Mikhaĭlov, I.V.; Iakovlev, V.M. 1993: Effect of acute hypoxia on the phospholipid composition of the cell, microsomal and mitochondrial membranes of rat brain and liver Voprosy Meditsinskoi Khimii 39(5): 50-52