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The effect of ginseng stem, leaf and rhizoma saponins on the formation of lipid peroxides in rats of various ages

Sun, W.J.; Ma, N.; Ma, L.X.; Zhang, Y.L.; Feng, W.L.

Zhongguo Zhong Yao Za Zhi 14(5): 300

1989

ISSN/ISBN: 1001-5302
PMID: 2512949
Document Number: 329406
The effect of saponins isolated from the stem, leaf and rhizome of Panax ginseng on the formation of lipid peroxides in aged (30, 24 end 20 months) and middle-aged (14 months) wistar rats was studied with both in vivo and in vitro methods. The formation of lipid peroxides increased with age in rats and mice; the two saponins of ginseng stem, leaf and rhizome can obviously inhibit the lipid peroxidation in the serum (plasma) and liver homogenate of aged and middle-aged rats (p < 0.05 and < 0.001). The same effect was also shown in the aged LACA mouse (18 months) experiment.

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