Lipid peroxidation in the tissues of rats of different ages normally and during fasting
Gatsko, G.G.; Mazhul', L.M.; Pozdniakova, E.A.
Biulleten' Eksperimental'noi Biologii i Meditsiny 93(4): 30-32
1982
ISSN/ISBN: 0365-9615 PMID: 7082798 Document Number: 184159
Experiments on male rats aged 4-6 and 24-26 months have shown that the concentration of malonic dialdehyde (MDA) increases with aging. Forty-eight-hour fasting lowers the MDA content in all the samples examined (blood serum, liver, adipose tissue) of old rats. No changes have been found in young rats. It is suggested that retardation of lipid peroxidation caused by fasting might be associated with antioxidative system activation.