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Effect of the water-soluble antioxidant hydroxypyridine-6 on the intensity of lipid peroxidation in eye tissues in experimental ophthalmic herpes

Kasavina, B.S.; Maĭchuk, I.F.; Dalgat, L.D.; Romashchenko, A.D.

Biulleten' Eksperimental'noi Biologii i Meditsiny 94(7): 27-28

1982

ISSN/ISBN: 0365-9615
PMID: 7126819
Document Number: 188167
Lipid peroxidation (LPO) in eye tissues of rabbits with experimental herpetic keratitis was evaluated from the malonic dialdehyde content and chemiluminescence intensity. It appeared that during the critical phase LPO sharply increased in all the tissues under study and in anterior chamber humor. After administration of the synthetic water-soluble antioxidant, hydroxypyridine-6 the subconjunctival content of malonic dialdehyde and chemiluminescence intensity approached normal values accompanied by positive therapeutic effect.

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