Anti-edematous action of EDTA, its effect on lipid peroxidation intensity and various components of the antioxidant system of the lungs in rats exposed to NO2
Galkin, B.N.; Golovenko, N.I.; Ostrov, V.E.; Filippova, T.O.; Tikhonov, A.V.; Barinov, V.A.; Chernienko, I.E.
Ukrainskii Biokhimicheskii Zhurnal 67(4): 92-95
1995
ISSN/ISBN: 0201-8470 PMID: 8553480 Document Number: 440896
It has been studied how preventive administration of EDTA influences toxic NO2- induced pulmonary edema and disturbances in antioxidant systems. The compound in question, being preventively administered, has exerted a significant antiedematic effect as a result of a decrease in lipid peroxidation intensity and protection of the most important substrate components of the nonenzymatic antioxidant system from the oxidation effect.