Lipid peroxidation and enzymes of the antioxidant defense system in patients with bronchial asthma

Abdullaev, S.F.; Inoiatov, F.S.

Likars'ka Sprava 2: 28-31

2003


ISSN/ISBN: 1019-5297
PMID: 12774469
Document Number: 561216
In 71 patient with bronchial asthma (BA), lipid peroxidation (LPO) was studied together with the condition of the antioxidant system (AOS) as related to the degree of severity of the illness, with results evaluated of conventional therapy versus complex treatment involving the use of cytochrome C. Established in the above series was intensification of LPO in the presence of inhibition of activity of SOD enzymes and catalase, their degree dependent on severity of the condition. Unlike basic therapy, employment of cytochrome C has been found to be associated with a more complete restoration of balance in the LPO/AOS system, especially so in steroid-independent form of BA.

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