Characteristics of the functional state of the pancreas, lipid peroxidation and antioxidant defense in food hypersensitivity in children
Dorofeeva, G.D.; Bondar', L.S.; Lepikhov, P.A.; Prilutskiĭ, A.S.
Pediatriia 3: 18-22
1992
ISSN/ISBN: 0031-403X PMID: 1513645 Document Number: 393610
Pancreas function, lipid peroxidation and antioxidant defence were studied in 154 children aged 1 to 14 years with food allergy. Allergic inflammation due to food allergy favours the origin of different abnormalities of pancreas function: functional (39.4%), reactive pancreatitis (31.3%), chronic pancreatitis (20.1%), and sclerosing chronic pancreatitis (9.2%). They occur in combination with lipid peroxidation activation and a decrease in antioxidant defence. The intensity of the latter ones is dependent on the variety of pancreas function disturbance. The most significant changes in lipid peroxidation and antioxidant defence were discovered in chronic pancreatitis.