Phenthiuram induction of micronuclei in mammalian somatic cells
Bakhitova, L.M.; Pashin, I.V.
Tsitologiia i Genetika 21(1): 54-57
1987
ISSN/ISBN: 0564-3783 PMID: 2436363 Document Number: 291420
Genotoxic effects of the preparative-form phenthiuram on the induction of micronuclei in cultured Chinese hamster V-79 cells and polychromatic erythrocytes of mouse bone marrow have been studied. The phenthiuram induced cytogenetic effects in cultured somatic cells without metabolic activation being only in toxic concentrations. Similar effects were observed in polychromatic erythrocytes after treatment with subtoxic concentrations.
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