Cloning of asexual blood-stage antigens of Plasmodium falciparum
Coppel, R.L.; Crewther, P.E.; Favaloro, J.M.; Stahl, H.D.
Papua and New Guinea Medical Journal 29(1): 75-80
1986
ISSN/ISBN: 0031-1480 PMID: 3463017 Document Number: 278543
Recombinant DNA technology has enabled the generation of bacteria capable of synthesizing P. falciparum proteins. This allows purified and characterized protein antigens to be tested for possible protective effect. Several antigens have been identified as promising candidate vaccine molecules and current progress in cloning them is reviewed.
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