Influence of the asexual parasite biomass on in vitro susceptibility of Plasmodium falciparum to antimalarial drugs in Abidjan

Brice,B.K.; William,Y.; Lacinan,O.; Leonardo,B.; Joseph,D.A.

African Journal Of Biotechnology: 8, 936-940. Ef

2008


ISSN/ISBN: 1684-5315
Document Number: 200465
The in vitro activities of artemisinin, dihydroartemisinin (the biologically active metabolite of artemisinin derivatives), chloroquine and pyronaridine were assessed in 32 isolates of Plasmodium falciparum from Abobo in the northern of Abidjan district (Cote d'Ivoire) using a test based on the standard microtechnique recommended by the World Health Organization (WHO). The parasites densities were ranged between 8,000 and 540 000 rings/ micro l of blood.

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