A bovine haemagglutinin of Bordetella bronchiseptica responsible for adherence
Semjén, G.; Magyar, T.
Acta Veterinaria Hungarica 33(3-4): 129-136
1985
ISSN/ISBN: 0236-6290 PMID: 2940833 Document Number: 252770
Bordetella bronchiseptica strains freshly isolated from swine herds with atrophic rhinitis (AR) showed a similar hemagglutination pattern including agglutination of calf erythrocytes (calf-positive strains). After several passages these strains lost the ability to agglutinate calf and horse red blood cells (RBCs) but retained hemagglutinating activity on RBCs from other animal species (calf-negative strains). Phase III strains failed to agglutinate calf RBCs; neither did they agglutinate sheep erythrocytes. In the in vitro experiment, calf-positive strains attached to the cilia of epithelial cells, whereas calf-negative variants failed to do so. It is postulated that this new type of hemagglutinin in B. bronchiseptica strains may act as an adhesin and as a virulence factor in the pathogenesis of AR in swine.