Serological response of cattle to simultaneous vaccinations against foot-and-mouth disease and haemorrhagic septicaemia
Joseph, P.G.; Hedger, R.S.
Veterinary Record 114(20): 494-496
1984
ISSN/ISBN: 0042-4900 PMID: 6330961 Document Number: 240527
In Malaysia, where vaccination campaigns against foot and mouth disease and haemorrhagic septicaemia are routinely carried out, it was desirable to determine whether it was safe and efficacious to administer the two vaccines simultaneously. A trial group of 104 cattle was divided into three groups: group 1 animals received the vaccines simultaneously, group 2 animals received only FMD vaccine, and group 3 animals received only haemorrhagic septicaemia vaccine. The serological response to vaccinations was monitored at 0, 21 and 35 days by the virus neutralization test for FMD disease and the mouse-protection and indirect haemagglutination tests for haemorrhagic septicaemia. The simultaneous administration of the two inactivated vaccines produced no adverse effects and the serological response did not differ from the response to either vaccine given separately, thus indicating that cattle may be safely and effectively vaccinated simultaneously in this way.