Top Abstract Purchase Related
Home
>
Node
>
Subnode

Change in the properties of plasma membranes of normal and neoplastic cells after incorporation of cholesterol

Ivanova, L.I.; Khalilov, E.M.; Archakov, A.I.; Lopukhin, I.M.

Biulleten' Eksperimental'noi Biologii i Meditsiny 97(4): 450-452

1984

ISSN/ISBN: 0365-9615
PMID: 6326887
Document Number: 231187
It is shown that cholesterol incorporation into the membranes of lymphocytes, lymphoblast leikose cells L1210 and into those of ovary tumor causes an increase in the membrane phospholipid bilayer microviscosity measured by pyrene as a fluorescent probe. An increase in the membrane lipid microviscosity resulted in a decrease in the activity of Na+, K+-ATPase and 51-nucleotidase of the normal and tumor cells. After the injection of the tumor cells with an elevated cholesterol/phospholipid ratio an increase of the life span in the experimental animals as compared with the control group was observed.

Document emailed within 1 workday
Secure & encrypted payments

Davydova, S.I.; Shapot, V.S. 1972: Structural components of plasma membranes of normal and neoplastic animal cells Biokhimiia 37(4): 807-812
Stoĭda, L.V. 1983: Change in the molecular properties of sarcoplasmic reticulum Ca-ATPase during modification of the membranes with cholesterol Biulleten' Eksperimental'noi Biologii i Meditsiny 96(10): 38-40
Anderson, K.C.; Bates, M.P.; Slaughenhoupt, B.; Schlossman, S.F.; Nadler, L.M. 1984: A monoclonal antibody with reactivity restricted to normal and neoplastic plasma cells Journal of Immunology 132(6): 3172-3179
Wu, X.; Fu, M.; Lan, D.; Liu, B.; Zhou, J.; Deng, P. 1999: Effect of human plasma HDL on the HDL receptors of plasma membranes of cholesterol-fed rabbit Hua Xi Yi Ke da Xue Xue Bao 30(4): 370-372
Borodin, E.A.; Dobretsov, G.E.; Karasevich, E.I.; Karuzina, I.I.; Kariakin, A.V. 1981: Effect of incorporation and removal of cholesterol on the lipid bilayer viscosity and the rate of oxidative reactions in rat liver microsomal membranes Biokhimiia 46(6): 1109-1118
Nanji, A.A. 1982: Intercorrelations between normal concentrations of glucose, triglycerides, total cholesterol, high-density lipoprotein cholesterol, and uric acid in plasma during fasting Clinical Chemistry 28(5): 1242-1243
Ohsawa, T. 1980: Change in permeability of liposomal membranes mediated by C-reactive protein and its inhibition by cholesterol Japanese Journal of Experimental Medicine 50(1): 67-71
Koletsky, A.J.; Harding, M.W.; Handschumacher, R.E. 1986: Cyclophilin: distribution and variant properties in normal and neoplastic tissues Journal of Immunology 137(3): 1054-1059
Torkhovskaia, T.I.; Gorbatenkova, E.A.; Dudaev, V.A.; Chesnokova, I.M.; Azizova, O.A. 1986: Cholesterol-acceptor properties of high-density lipoproteins with respect to erythrocyte membranes in patients with ischemic heart disease Voprosy Meditsinskoi Khimii 32(2): 101-105
Usatiuk, S.A.; Kurs'kyĭ, M.D. 1995: Structure and functional properties of GTP-binding proteins of plasma membranes Ukrainskii Biokhimicheskii Zhurnal 67(1): 14-25
Shlykov, S.G.; Slinchenko, N.N.; Kurskiĭ, M.D. 1987: Properties of adenylate cyclase from plasma membranes of the rabbit myometrium in different functional states Ukrainskii Biokhimicheskii Zhurnal 59(1): 82-86
Mason, D.Y.; Cordell, J.L.; Tse, A.G.; van Dongen, J.J.; van Noesel, C.J.; Micklem, K.; Pulford, K.A.; Valensi, F.; Comans-Bitter, W.M.; Borst, J. 1991: The IgM-associated protein mb-1 as a marker of normal and neoplastic B cells Journal of Immunology 147(11): 2474-2482
Roslyĭ, I.M. 1976: Characteristics of 21S and 7,5S RNP particles from cytoplasm of normal and neoplastic cells Voprosy Meditsinskoi Khimii 22(1): 113-116
Vojtĕsek, B. 1997: Study of p53 anti-oncogene in normal and neoplastic cells Casopis Lekaru Ceskych 136(23): 11-13
Matsuoka, H.; Furusawa, M.; Tomoda, H.; Seo, Y. 1994: Difference in cytotoxicity of paclitaxel against neoplastic and normal cells Anticancer Research 14(1a): 163-167
Vdovichenko, V.I. 1970: Effect of tetracycline on respiration and glycolysis of normal and neoplastic cells Antibiotiki 15(10): 928-930
Davydov, B.V.; Chebotarev, A.A.; Polumiskov, V.Iu.; Golikov, A.P.; Golikov, P.P. 1985: Change in the alpha-tocopherol content of blood plasma and erythrocyte membranes in patients with myocardial infarct in the acute period Kardiologiia 25(7): 109-111
Kazhdan, I.I.; Tsveĭbakh, A.S. 1988: Possible mechanisms regulating the entry of normal and neoplastic cells into the DNA synthesis phase Tsitologiia 30(5): 516-523
Stavrovskaia, A.A.; Kakpakova, E.S.; Stromskaia, T.P. 1973: Comparative sensitivity of normal and neoplastic cells to the mitostatic action of colcemid Tsitologiia 15(6): 739-745
Feldman, M.Y.; Balabanova, H.; Bachrach, U.; Pyshnov, M. 1977: Effect of hydrolyzed formaldehyde-treated RNA on neoplastic and normal human cells Cancer Research 37(2): 501-506