Change in permeability of liposomal membranes mediated by C-reactive protein and its inhibition by cholesterol

Ohsawa, T.

Japanese Journal of Experimental Medicine 50(1): 67-71

1980


ISSN/ISBN: 0021-5031
PMID: 7382134
Document Number: 164104
CRP-positive human serum specifically releases the trapped glucose from multilamellar liposomes composed of egg lecithin and dicetylphosphate. The release is dependent on Ca++ ion and is suppressed by incorporation of cholesterol into liposomes membranes. A specific role of cholesterol in CRP-receptor recognition at membranes of immunocytes is suggested.

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