Production of IFN beta with human fibroblasts in monolayer cultures. Comparative studies of induction with virus (NDV) and synthetic polynucleotides (poly i - poly C)
Frappa, J.; Trotemann, P.; Beaudry, Y.; Fontanges, R.
Developments in Biological Standardization 50: 185-192
1981
ISSN/ISBN: 0301-5149 PMID: 6176485 Document Number: 178700
A comparative study of the production of IFN beta by human skin fibroblasts in monolayers was carried out using induction by NDV and poly I - poly C. The induction by polynucleotides produced significantly higher IFN beta titers. An attempt to grow those diploid cells on microcarriers resulted in a failure.
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