Swine vesicular disease viruses isolated from healthy pigs in non-epizootic period. II. Vesicular formation and virus multiplication in experimentally inoculated pigs
Kodama, M.; Saito, T.; Ogawa, T.; Tokuda, G.; Sasahara, J.; Kumagai, T.
National Institute of Animal Health Quarterly 20(4): 123-130
1980
ISSN/ISBN: 0027-951X PMID: 6267484 Document Number: 158938
Conventionally managed pigs were inoculated with six strains of swine vesicular disease virus isolated from healthy pigs. Inoculation was oral or intradermal in the coronary band. Oral inoculation produced milk transient pyrexia in two of 11 pigs. Intradermal inoculation produced mild pyrexia in three of 15 pigs and vesicular formation in eight. The vesicles lasted 2-5 days, followed by rapid repair. Some strains caused viraemia which was mild. Neutralizing antibody titres reached a peak 10 days after inoculation.