Effect of K and Mg salts of aspartic acid on haemopoiesis and recovery from radiation damage in mice

Pospísil, M.; Netíková, J.; Pipalová, I.; Mikeska, J.

Folia Biologica 26(1): 53-61

1980


ISSN/ISBN: 0015-5500
PMID: 7364133
Document Number: 155654
Male mice of a non-inbred strain "H" were used to verify the effect of a 10-day peroral administration of K and Mg aspartates on haemopoietic functions. The salts were proved to stimulate the proliferation and differentiation processes in the thymus, bone marrow and spleen tissues. Mice exposed to a single whole-body X-irradiation after pretreatment with K, Mg aspartate exhibited a more conspicuous postirradiation regeneration of haemopoietic organs and an increased postirradiation survival. The results suggest the possibility of using K, Mg aspartate for radioprotective purposes.

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