Canine bordetellosis: chemotherapy using a sulphadiazine-trimethoprim combination
McCandlish, I.A.; Thompson, H.
Veterinary Record 105(3): 51-54
1979
ISSN/ISBN: 0042-4900 PMID: 555120 Document Number: 146512
Respiratory disease was induced in young dogs by exposure to an aerosol of Bordetella bronchiseptica. The affected dogs were then treated with a sulfadiazine-trimethoprim combination by daily subcutaneous injection for five days. There was obvious improvement in the clinical, bacteriological and pathological features of the respiratory disease during and immediately after the treatment period, but treated dogs relapsed a few days after chemotherapy was stopped. Treatment for a longer period may be of value in the treatment of dogs with respiratory disease associated with this bacterium.