Enanthema fixum as side effect in the use of a combination of trimethoprim and sulfamethoxazole
Arifhodzić, F.; Rajman, I.; Petronijević, S.; Ivković, B.
Vojnosanitetski Pregled 49(1): 30-32
1992
ISSN/ISBN: 0042-8450 PMID: 1595229 Document Number: 4080
Cases of fixed drug eruption due to trimethoprim-sulfamethoxazole combination are reported. In these cases the oral mucous membranes were affected. Fixed drug eruption is a distinct entity characterized by the development of circular erythematous lesions which over a period of time becomes violaceous. Sulfamethoxazole is probably the main cause of this drug eruption but there are some reports that trimethoprim itself can cause them too.
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