Comparison of trimethoprim-sulfamethoxazole with sulfamethoxazole in urinary tract infections of children
Feldman, W.; Johnson, D.M.; Newberry, P.; Weldon, A.; Naidoo, S.
Canadian Medical Association Journal 112(13 Spec No): 19-21
1975
ISSN/ISBN: 0008-4409 PMID: 1093648 Document Number: 90105
The effect of trimethorpim-sulfamethoxazole was compared with that of sulfamethoxazole alone in 26 children with urinary tract infection, randomly assigned according to a double-blind procedure to two equally sized groups. TMX-SMX was found to be superior in rendering the urine culture negative for the 3 months after the start of treatment. Also, over 12-month follow-up period there were fewer recurrences in the patients who received TMP-SMX but here the difference between the two groups did not reach statistical significance.