The retrograde transport of horseradish peroxidase: problems in the interpretation of its ultrastructural aspects
Gazzanelli, G.; Marelli, M.; Franceschini, F.; Amati, S.; Osculati, F.
Bollettino della Societa Italiana di Biologia Sperimentale 55(4): 383-389
1979
ISSN/ISBN: 0037-8771 PMID: 399735 Document Number: 141857
In this study we consider critically the use of HRP in research on the ultrastructure of the Central Nervous System. In fact, although controls make by optical microscope on semi-thin sections made us certain that some of the neurons were definitely marked with the enzyme, when the same specimen was observed by electron microscope, in no case was it possible for us to distinguish any particular aspect of the ultrastructural morphology of labelling within neurons.