Toxicological properties of a cephedrine preparation
Pashinskiĭ, V.G.; Vysokovskiĭ, T.M.; Khlienko, Z.N.; Aref'eva, A.K.; Ponomareva, L.F.
Farmakologiia i Toksikologiia 41(3): 345-347
1978
ISSN/ISBN: 0014-8318 PMID: 658386 Document Number: 127303
The antidepressant drug cephedrine experimentally displays a little acute and chronic toxicity, does not influence the development of allergic reaction in guinea pigs, changes but little the ECG and does not possess teratogenic and embryotoxic properties. When used in a subtoxic dose it is capable of causing dystrophic changes in individual neurons in the cortex and subcortical formations of the central nervous system, to delay the growth of fetuses, especially when administered during the second half of gestation.