Use of the "graft vs host" reaction to study the immunosuppressive effect of methylenediphosphonic acid
Komissarenko, S.V.; Karlova, N.P.
Fiziolohichnyi Zhurnal 23(6): 786-788
1977
ISSN/ISBN: 0015-3311 PMID: 22464 Document Number: 123615
The graft vs. host reaction was used to study methylene diphosphonic acid immunosuppresive activity. Methylene diphosphonic acid was injected 3 .times. in a dose of 40 .mu.g/g of body wt to BALB/c mice, the source of donor spleen cells. The graft vs. host reaction in F1 (BALB/c .times. 57B1) after transplantation of living BALB/c spleen cells was inhibited.