Effect of antimacrophage serum on the graft vs. host reaction in F1 hybrid mice
Kenarova, B.
Eksperimentalna Meditsina i Morfologiia 18(4): 216-219
1979
ISSN/ISBN: 0367-0643 PMID: 42526 Document Number: 151368
The author carried out experiments on 100 one-week old F1 hybrids (BALB-C C57-BL) and succeeded to obtain moderately manifested CvH reaction, injecting them with peritoneal macrophages from one of the parent's lines-BALB-C, immunized preliminary with lymphocytes from other parentalline. Preliminary incubation of macrophages with AMC without participation of compliment did not affect significantly the manifestations of GvH reaction, while successive incubation of macrophages with AMC and compliment inhibited completely the ability of the cells to induce GvH reaction. This effect was in correlation with the vitality of the cells.