Hemolytic activity of a lipid material obtained from peroxidized microsomes
Willis, R.J.; Pesh-Imam, M.; Recknagel, R.O.
Research Communications in Chemical Pathology and Pharmacology 18(3): 433-437
1977
ISSN/ISBN: 0034-5164 PMID: 22110 Document Number: 118725
Lipid peroxidation was induced in rat liver microsomes by the addition of NADPH. When mixed with red cells in the presence of EDTA, these peroxidized microsomes caused hemolysis. All of the hemolytic activity of peroxidized microsomes could be extracted with lipid solvents and recovered as an aqueous lipid emulsion.
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