Contribution to stability test of daunoblastin solutions
Projan, A.; Nissen, E.
Archiv für Geschwulstforschung 46(1): 50-57
1976
ISSN/ISBN: 0003-911X PMID: 962502 Document Number: 109672
It is known that drugs are not unlimitedly stable. Dilutions of the antineoplastic agent daunoblastin used in the clinic and experimental work, were examined, whether they could be stored for several days. By means of impulscytophotometry, spectral-photometric measurements, counting of surviving cells and estimation of DNA-synthesis after culturing pieces of tissue in the presence of daunoblastin it could be established that this drug, diluted even four days ago, still possesses sufficient activity.