Azide-dependent mutants in E. coli K12
Daniel, J.
Nature 264(5581): 90-92
1976
ISSN/ISBN: 0028-0836 PMID: 794730 Document Number: 98810
Sodium azide is known specifically to inhibit or activate a number of enzymatic activities from bacteria1 and from higher organisms2,3. Furthermore it has been shown that azide can inhibit the Mg2+-dependent ATPase of Escherichia coli in vivo4 at concentrations that do not produce any deleterious uncoupling effects on the membrane energy-transducing apparatus of the cell5. We felt that those facts could provide the basis for searching out a new type of mutation in E. coli - azide dependency.
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