Occurrence of induced vitamin-dependent mutants of Yersinia pestis
Khozova, N.A.; Suchkov, I.G.
Genetika 13(11): 2053-2055
1977
ISSN/ISBN: 0016-6758 PMID: 614956 Document Number: 123097
Vitamin-dependent mutants were isolated from Yersinia pestis after the treatment with supermutagens. From 13 mutants obtained 10 appeared to be unstable. The stable vitamin-dependent mutants were revealed with the frequency of 2.5.10(-11) divided by 4.9.10(-11) by the indirect method of selection and 5.10(-7) by the use of Davis's method. The frequency of amino acid and nitrogen base dependent auxotroph isolation was significantly higher than that of the vitamin-dependent mutants.
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