Top Abstract Purchase Related
Home
>
Node
>
Subnode

Role of radiosensitivity and radioresistance genetic markers in hematological and cardiovascular disease in persons exposed after the Chornobyl accident

Minchenko, J.M.; Dyagil, I.S.; Dmytrenko, O.O.; Dmytrenko, I.V.; Shlaykhtychenko, T.Y.; Gavrylenko, T.I.; Biliy, D.O.; Khomenko, V.I.; Bebeshko, V.G.

Problemy Radiatsiinoi Medytsyny Ta Radiobiolohii 18: 220-231

2013

ISSN/ISBN: 2304-8336
PMID: 25191726
Document Number: 664796
Meta roboty poljagala u vyvchenni vnesku imunogenetychnoi' komponenty v formuvannja postradiacijnyh efektiv u viddalenomu periodi pislja oprominennja na rivni imunnogo reaguvannja organizmu ljudyny, jak prognostychnogo kryteriju ocinky ryzyku realizacii' radiacijno-asocijovanoi' somatychnoi' patologii'. Ob'jektom doslidzhennja buly rekonvalescenty gostroi' promenevoi' hvoroby (GPH) I stupenja tjazhkosti i 88 pacijentiv z analogichnym radiacijnym anamnezom, ale z nepidtverdzhenym diagnozom GPH, 73 pacijenty, jaki majut' status uchasnykiv likvidacii' naslidkiv Chornobyl's'koi' katastrofy (ULNChK) z hronichnoju ishemichnoju hvoroboju sercja (HIHS), 65 pacijentiv – ULNChK bez HIHS, 120 neoprominenyh pacijentiv z HIHS. Pacijenty z onkogematologichnoju patologijeju – 256 osib. 500 praktychno zdorovyh osib – populjacijnyj kontrol'. Rezul'taty. Na osnovi vyvchennja spektru imunologichnyh, gematologichnyh ta molekuljarno-genetychnyh porushen' u spivvidnoshenni z imunogenetychnymy chynnykamy vyznacheni markery ryzyku realizacii' genetychnoi' shyl'nosti do onkogematologichnoi' ta sercevo-sudynnoi' patologii' u zaznachenyh kontyngentiv. Vysnovky. Otrymani dani svidchat' pro te, shho odnym iz mehanizmiv formuvannja radiacijno-asocijovanoi' mul'tyfaktorial'noi' patologii', je realizacija HLA-genetychnoi' shyl'nosti do zahvorjuvannja, jak na rivni rozladiv u gemopoezi ta imunopoezi, tak i na rivni zahvorjuvannja v cilomu, a nosijstvo v feno/genotypi markeriv radiochutlyvosti pidvyshhuje ryzyk realizacii' patologichnogo procesu v umovah oprominennja.

Document emailed within 1 workday
Secure & encrypted payments

Guslitser, N.; Zavelevich, M.P.; Koval, S.V.; Gluzman, D.F. 2016: Several aspects of descriptive epidemiology of hematological malignancies in adult population of Ukraine, Belarus and Russian Federation after Chornobyl accident Experimental Oncology 38(4): 211-218
Shkarupa, V.M.; Henyk-Berezovska, S.O.; Neumerzhytska, L.V.; Klymenko, S.V. 2014: Allelic polymorphism of DNA repair gene XRCC1 in patients with thyroid cancer who were exposed to ionizing radiation as a result of the Chornobyl accident Problemy Radiatsiinoi Medytsyny Ta Radiobiolohii 19: 377-388
Shkarupa, V.M.; Mishcheniuk, O.Y.; Henyk-Berezovska, S.O.; Palamarchuk, V.O.; Klymenko, S.V. 2016: Polymorphism of DNA repair gene XPD Lys751Gln and chromosome aberrations in lymphocytes of thyroid cancer patients exposed to ionizing radiation due to the Chornobyl accident Experimental Oncology 38(4): 257-260
Bebeshko, V.G.; Bruslova, K.M.; Tsvietkova, N.M.; Volodina, T.T.; Kopylova, O.V.; Belingio, T.O.; Berezovski, S.A.; Petrunko, M.P.; Boyarskiy, V.G.; Polianska, V.M.; Pushkareva, T.I.; Mishchenko, L.P. 2014: Rationale treatment and preventive measures for correction of bone structure in children with acute leukemia, exposed to ionizing radiation due to the Chornobyl accident Problemy Radiatsiinoi Medytsyny Ta Radiobiolohii 19: 192-202
Ilyenko, I.M. 2013: Role of VEGF-A gene in the formation of late effects after the Chornobyl accident Problemy Radiatsiinoi Medytsyny Ta Radiobiolohii 18: 190-199
Umovist, N.M.; Zhaboedov, G.D.; Niagu, A.I.; Novitskiĭ, A.N.; Davidenko, F.F. 1991: State of the organ of vision in persons exposed to radiation in connection with the Chernobyl AES accident Vestnik Akademii Meditsinskikh Nauk SSSR 1991(11): 48
Ivanitskaia, N.F. 1992: Neuroendocrine disorders at long term in persons exposed to ionizing radiation after the accident at the Chernobyl Atomic Electric Power Station Likars'ka Sprava 1: 35-37
Chekhovich, A.V.; Pomerantseva, M.D.; Ramaĭia, L.K.; Shevchenko, V.A. 1993: Genetic disorders in laboratory mice, exposed in the region of the Chernobyl Atomic Power Plant four years after the accident Genetika 29(2): 312-322
Tsyb, A.F.; Ivanov, V.K.; Aĭrapetov, S.A.; Gagin, E.A.; Maksiutov, M.A.; Rozhkov, O.V.; Stadnik, O.E.; Chekin, S.I.; Saakian, A.K. 1991: Radiation-epidemiologic analysis of the data of State Registry of persons exposed to radiation due to the Chernobyl AES accident Vestnik Akademii Meditsinskikh Nauk SSSR 11: 32-36
Pilinskaia, M.A.; Shemetun, A.M.; Dybskiĭ, S.S.; Red'ko, D.V. 1996: The genetic effects in the somatic cells of persons working under chronic irradiation of different intensities after the accident at the Chernobyl Atomic Electric Power Station Tsitologiia i Genetika 30(2): 17-25
Medvedev, V.P. 1973: Diseases of the cardiovascular system in persons exposed in the past to the action of a superhigh frequency electromagnetic field Gigiena Truda i Professional'nye Zabolevaniya (3): 6-9
Bazyka, D.A.; Gudzenko, N.A.; Dyagil, I.S.; Babkina, N.G.; Chumak, V.V.; Bakhanova, E.V.; Paramonov, V.V.; Romanenko, A.Y. 2013: Multiple myeloma among Chornobyl accident clean-up workers - state and perspectives of analytical study Problemy Radiatsiinoi Medytsyny Ta Radiobiolohii 18: 169-172
Casasnovas, J.A.; Puzo, J.; Garza, F.; Lapetra, A.; Elosegui, L.M.; Del Rio, A.; Giner, A.; Escanero, J.F.; Ferreira, I.J. 1988: Hematological indices as markers of ischemic heart disease in young smokers Biomedicine and PharmacoTherapy 42(2): 99-100
Mishcheniuk, O.Y.; Klymenko, S.V. 2013: Clinical risk factors of thrombosis in patients with Ph-negative myeloproliferative neoplasms, who had experienced radiation exposure due to the Chornobyl accident Problemy Radiatsiinoi Medytsyny Ta Radiobiolohii 18: 232-239
Prysyazhnyuk, A.Y.; Fuzik, M.M.; Gudzenko, N.A.; Bazyka, D.A.; Fedorenko, Z.P.; Ryzhov, A.Y.; Sumkina, O.V.; Trotsyuk, N.K.; Khukhrianska, O.M. 2015: Experience of study of the incidence of malignant neoplasms population in small areas of Ukraine, which suffered contamination with radionuclides due to the Chornobyl accident Problemy Radiatsiinoi Medytsyny Ta Radiobiolohii 20: 229-240
Gunko, N.V.; Korotkova, N.V.; Omelyanets, N.I. 2016: Structural characteristics of children and adolescents at the time of the Chornobyl nuclear power plant accident residing in the most intensively contaminated territories of Ukraine Problemy Radiatsiinoi Medytsyny Ta Radiobiolohii 21: 132-140
Kaminskyi, O.V.; Kopylova, O.V.; Afanasyev, D.E.; Pronin, O.V. 2015: Non cancer thyroid and other endocrine disease in children and adults exposed to ionizing radiation after the ChNPP accident Problemy Radiatsiinoi Medytsyny Ta Radiobiolohii 20: 341-355
Fuzik, M.M.; Prysyazhnyuk, A.Y.; Shibata, Y.; Romanenko, A.Y.; Fedorenko, Z.P.; Gudzenko, N.A.; Gulak, L.O.; Trotsyuk, N.K.; Goroh, Y.L.; Khukhrianska, O.M.; Sumkina, O.V.; Saenko, V.A.; Yamashita, S. 2013: Age and gender patterns of thyroid cancer incidence in Ukraine depending on thyroid radiation doses from radioactive iodine exposure after the Chornobyl NPP accident Problemy Radiatsiinoi Medytsyny Ta Radiobiolohii 18: 144-155
Pavliuk, R.P.; Baĭ, O.N. 1996: The role of genetically determined blood system markers in the development of humoral immunity disorders in those who worked in the cleanup of the aftermath of the accident at the Chernobyl Atomic Electric Power Station Likars'ka Sprava 1996(7-9): 44-47
Kassem, N.S.; Mokhtar, M.M.; Elbel-Bessy, M.F. 1994: Genetic markers in coronary heart disease Journal of the Egyptian Public Health Association 69(5-6): 359-378