Chemical constituents of Acorus calamus
Qiao, D.; Gan, L.-S.; Mo, J.-X.; Zhou, C.-X.
Zhongguo Zhong Yao Za Zhi 37(22): 3430-3433
2012
ISSN/ISBN: 1001-5302 PMID: 23373216 Document Number: 663031
To study the chemical constituents contained in Acorus calamus. The chemical constituents were separated and purified by various chromatographic methods including silica gel, ODS, HPLC and Sephadex LH-20, and their structures were identified on the basis of analysis on spectroscopic data. Ten compounds were separated from A. calamus and identified as 1beta, 4beta, 7alpha-trihydroxyeudesmane (1), bullatantriol (2), teuclatriol (3), threo-1', 2'-dihydroxyasarone (4), erythro-1', 2'-dihydroxyasarone (5), (+)-de-4'-O-methyleudesmin (6), (+)-de-4'-0-methylmagnolin (7), (+)-eudesmin (8), (+)-magnolin (9) and beta-sitosterol (10), respectively. Compounds 1-2,4-9 were separated from this plant for the first time. Specifically, compounds 1-2,6-9 were obtained from Acorus genus for the first time.