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Chemical constituents of Ligularia dictyoneura

Tan, A.-m.; He, H.-p.; Yang, H.; Zhang, M.; Wang, Z.-t.; Hao, X.-j.

Yao Xue Xue Bao 38(12): 924-926

2003

ISSN/ISBN: 0513-4870
PMID: 15040086
Document Number: 563699
To study the chemical constituents of Ligularia dictyoneura. Various chromatographic techniques were used to separate and purify the compounds. Their spectral data (MS, IR, NMR) were measured for structure elucidation. Four sesquiterpenes were isolated from Ligularia dictyoneura and their structures were identified as ligudicin A (1), ligudicin C (2), ligudicin D (3) and isopetasin (4). Compound 1 is a new compound, compound 2 is a new natural product, and compounds 3 and 4 are obtained from Ligularia dictyoneura for the first time.

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