Scale-up of the fermentation of Leptospira interrogans canicola canicola for the production of vax-SPIRAL vaccine
Zamora, J.é D.B.ít.; Enrique, K.F.án.; Boué, R.úl.G.ér.; Torres, F.H.án.; Airado, J.L.; Hernández, D.án.R.
Revista Cubana de Medicina Tropical 57(1): 71-72
2005
ISSN/ISBN: 0375-0760 PMID: 17966489 Document Number: 592773
The operational conditions for the production of vaccine vax-SPIRAL were established at the scale of 100 L. It was concluded that it should be carried out with an air flow of 10 L/min (0.1 vvm) and without mechanical agitation.
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