New polycyclic azines derived from pyrazolo[3,4-b]pyridine
El-Emary, T.I.; Hussein, A.M.; el-Kashef, H.S.
Die Pharmazie 55(5): 356-358
2000
ISSN/ISBN: 0031-7144 PMID: 11828614 Document Number: 523404
The aminoimidazolinyl derivative 3 was synthesized using the pyrazole amino aldehyde 1 as a starting material. Compound 3 has been used as a key intermediate in the synthesis of the title compounds.
Document emailed within 1 workday
Related Documents
Komuro, M.; Hori, W.; Hotta, M.; Saitoh, S.; Ishida, R.; Uchida, H. 1992: Pharmacokinetics of the new antiplatelet agent 2-methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo[1,5-a]pyridine in laboratory animals Arzneimittel-Forschung 42(1): 55-59Momo, K.; Someya, K.; Tachiiri, T.; Mitsuoka, Y.; Nakamura, K.; Imai, S.; Ino, T.; Ohkubo, H. 1992: Effects of the new antiplatelet agent 2-methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo[1,5-a]pyridine on platelet aggregation and thrombosis in experimental animals Arzneimittel-Forschung 42(1): 32-39
Kozlovskaia, V.E.; Grishanova, A.I.; Mishin, V.M.; Liakhovich, V.V. 1992: The effect of pyridine and pyridine-N-oxide on the monooxygenase system of rat liver microsomes Biokhimiia 57(10): 1592-1596
Nantka-Namirski, P.; Balicki, R. 1974: Dipyridyls. 3. Reactions of pyridine-3- and pyridine 4-aldehydes with malononitrile Acta Poloniae Pharmaceutica 31(3): 271-278
Hasegawa, R.; Kimura, J.; Yaono, M.; Takahashi, S.; Kato, T.; Futakuchi, M.; Fukutake, M.; Fukutome, K.; Wakabayashi, K.; Sugimura, T. 1995: Increased risk of mammary carcinoma development following transplacental and trans-breast milk exposure to a food-derived carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), in Sprague-Dawley rats Cancer Research 55(19): 4333-4338
El-Bahaie, S.; Assy, M.G.; Hassanien, M.M. 1990: Synthesis and biological activity of some azoles and azines Die Pharmazie 45(10): 791-792
Tarasova, V.E.; Ul'ianova, L.A.; Iudina, O.I.; Gol'dberg, L.E.; Povarov, L.S.; Olsuf'eva, E.N.; Bychkova, E.N.; Shepelevtseva, N.G. 1990: Production and antineoplastic activity of new asymmetric azines on the rubomycin base Antibiotiki i Khimioterapiia 35(4): 21-24
Qin, X.-l.; Fan, J.; Xue, X.-d.; Tang, N.-j.; Zhang, L.-w. 2012: Correlation between atmospheric polycyclic aromatic hydrocarbons exposure and urinary hydroxyl metabolites of polycyclic aromatic hydrocarbons in elderly population in Tianjin, China Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 30(12): 908-912
Deng, X.; Liu, Q.; Liu, S.; Li, W.; Chen, Y.; Wen, Y.; Luo, Y. 2017: Determination of polycyclic aromatic hydrocarbons in girls and association between polycyclic aromatic hydrocarbons exposure and puberty timing Wei Sheng Yan Jiu 46(5): 743-748
Auzzi, G.; Cecchi, L.; Costanzo, A.; Pecori Vettori, L.; Bruni, F. 1978: Pyrazolo[3,4d][1,3]thiazine systems Il Farmaco; Edizione Scientifica 33(10): 799-806
Cecchi, L.; Colotta, V.; Filacchioni, G.; Melani, F.; Palazzino, G.; Galli, A. 1987: Synthesis and binding study on pyrazolo[4,5-c] [1,8]naphthyridines Il Farmaco; Edizione Scientifica 42(9): 671-680
Zabska, R.; Kołodziejczyk, A.; Sieklucka-Dziuba, M.; Morawska, D.; Kleinrok, Z. 1998: Synthesis and pharmacological screening of pyrazolo[3,4-c]pyridazine derivatives Acta Poloniae Pharmaceutica 55(4): 305-310
Gupta, P.P.; Srimal, R.C.; Avasthi, K.; Garg, N.; Chandra, T.; Bhakuni, D.S. 1995: Antiallergic activity of alkyl substituted pyrazolo[3, 4-d]pyrimidine (compound 88-765) Indian Journal of Experimental Biology 33(1): 38-40
Gatta, F.; Gradoni, L.; Lupardini, E.; Gramiccia, M.; Orsini, S. 1991: Synthesis and antileishmanial activity of some 1- or 2-(dihydroxyalkyl) and 3-(dihydroxyalkoxy)pyrazolo [3,4-d] pyrimidines Farmaco 46(1): 75-84
El-Feky, S.A.; Abd el-Samii, Z.K. 1996: Synthesis and antihypertensive activity of novel 1-(4-benzyl-1-phthalazinyl)-pyrazolo[3,4-d]pyrimidines Die Pharmazie 51(8): 540-543
Rádl, S.; Zikán, V.; Smejkal, F. 1985: Preparation of 4-phenoxy and 4-phenylthio derivatives of 1H-pyrazolo[3,4-b]-quinoline with an antiviral effect Ceskoslovenska Farmacie 34(3-4): 119-122
Junien, J.L.; Guillaume, M.; Lakatos, C.; Sterne, J. 1981: Bronchodilator and antiallergic properties of LA 2851 (2-4-diamino-7-methyl-pyrazolo (1,5-a) 1,3,5-triazine) Archives Internationales de Pharmacodynamie et de Therapie 252(2): 313-326
Mavel, S.; Rubat, C.; Coudert, P.; Privat, A.M.; Couquelet, J.; Tronche, P.; Bastide, P. 1993: Synthesis of new 5-substituted pyrazolo[1,5-d][1,2,4]-triazine derivatives and their analgesic, anti-inflammatory and antipyretic properties Arzneimittel-Forschung 43(4): 464-468
Malinka, W.; Sieklucka-Dziuba, M.; Rajtar-Cynke, G.; Gasior, M.; Kleinrok, Z. 1995: Synthesis and pharmacological study of some derivatives of pyrazolo[4,3-c]pyrido[3,2-c]-1,2-thiazine-5,5-dioxide, a novel heterocyclic ring system Farmaco 50(1): 29-35
Bruni, F.; Costanzo, A.; Selleri, S.; Guerrini, G.; Giusti, L.; Martini, C.; Lucacchini, A. 1993: Synthesis of 7-(2-dimethylaminovinyl) derivatives of pyrazolo[1,5-a] pyrimidines, as precursors of new tricyclic series. Binding studies of BDZ receptor Farmaco 48(2): 309-319