The nature and cause of hookworm anemia
Foster, A.0.; Landsberg, J.W.
American Journal of Hygiene 20(2): 259-290
1934
ISSN/ISBN: 0096-5294 Document Number: 519305
Hematologic studies on dogs infected with Ancylostoma caninum strongly indicate that hookworm anemia is mainly, if not entirely, the result of blood-loss, since (1) the blood-sucking capacity of hookworms is sufficient to account for the degree of anemia produced without any other causal factor; (2) hookworms produce the type of anemia (microcytic hypochromic) clinically associated with chronic hemorrhage; (3) the picture of a developing hookworm anemia can be paralleled by the periodic, artificial bleeding of uninfected animals; (4) the anemias resulting . both from hookworm infestation and from artificial blood-loss respond equally well to Fe administration; and (5) the anemia of hookworm disease in dogs is capable of self-compensation in cases of long-continued infection.