The mechanism of action and the nature of the factors inducing the formation of uncultivatable forms of Salmonella typhimurium
Gintsburg, A.L.; Romanova, I.M.; Alekseeva, N.V.; Kovalev, I.N.; Aliapkina, I.S.; Chegaeva, E.V.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 6: 3-8
1999
ISSN/ISBN: 0372-9311 PMID: 10876838 Document Number: 503465
Approaches to the study of gene expression in the process of transition and prolonged stay of bacterial cells in the uncultivated state have been worked out with the use of the methods of reverse transcription and polymerase chain reaction. The differential expression of genes pqi and stn has been shown to occur in the uncultivated forms of S. typhimurium. The factor inducing the process of the transition of Salmonella cells into the uncultivated state has been found out.