Characteristics of mutagenesis by bleomycin and adriamycin in Salmonella typhimurium: action of catalase

Ejchart, A.; Chłopkiewicz, B.

Acta Poloniae Pharmaceutica 53(5): 357-359

1996


ISSN/ISBN: 0001-6837
PMID: 9415210
Document Number: 6315
The influence of catalase activity in adriamycin and bleomycin mutagenesis was investigated in Salmonella typhimurium TA98 and TA102, respectively. The activity of catalase in bacterial cells was inhibited by sodium azide. Mutagenicity of both drugs was not changed in bacterial cells with depressed catalase activity.

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Characteristics of mutagenesis by bleomycin and adriamycin in Salmonella typhimurium: action of catalase