Top Abstract Purchase Related
Home
>
Node
>
Subnode

Intra-arterial injection therapy of mitoxantrone for locally advanced breast cancer

Ichikawa, W.; Osanai, T.; Shimizu, C.; Uetake, H.; Iida, S.; Yamashita, T.; Nishi, N.; Togo, S.; Miyanaga, T.; Nihei, Z.; Sugihara, K.

Gan to Kagaku Ryoho. Cancer and ChemoTherapy 25(9): 1333-1335

1998

ISSN/ISBN: 0385-0684
PMID: 9703821
Document Number: 495825
Mitoxantrone (MIT) is a new anthraquinone anticancer agent. We treated 14 patients with locally advanced breast cancer, 3 of which were inflammatory breast cancers, by pre-operative arterial injection of MIT. The treatment protocol was MIT 12 mg/m2 injected into both the internal mammary and the subclavian arteries with oral administration of 5'-DFUR 1,200 mg/day for 20 days. After 2 courses, all tumors were decreased over 50% in size. Down-staging was obtained in all of 8 cases. Mastectomy could be carried out on all patients, without microscopically residual tumor cells. Preoperative arterial injection of MIT might be the treatment of choice for locally advanced breast cancer to perform down-staging, however the survival benefit has remained equivocal. These preliminary results are encouraging to further studies.

Document emailed within 1 workday
Secure & encrypted payments

Ichikawa, W.; Nihei, Z.; Yamashita, T.; Sawai, S.; Shoji, Y.; Miyanaga, T.; Yoshinaga, K.; Hirayama, R.; Mishima, Y. 1993: Preoperative intra-arterial injection of mitoxantrone for locally advanced breast cancer Gan to Kagaku Ryoho. Cancer and ChemoTherapy 20(11): 1597-1600
Fiorentini, G.; Tsetis, D.; Bernardeschi, P.; Varveris, C.; Rossi, S.; Kalogeraki, A.; Athanasakis, E.; Dentico, P.; Kanellos, P.; Biancalani, M.; Almarashdah, S.; Zacharioudakis, G.; Saridaki, Z.; Chalkiadakis, G.; Xynos, E.; Zoras, O. 2003: First-line intra-arterial chemotherapy (IAC) with epirubicin and mitoxantrone in locally advanced breast cancer Anticancer Research 23(5b): 4339-4345
Inaji, H.; Noguchi, S.; Yamamoto, H.; Koyama, H.; Iwanaga, T.; Wada, A. 1989: Analysis of prognostic factors in patients with locally advanced breast cancer treated with intra-arterial infusion chemotherapy as an induction therapy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 16(8 Part 2): 2910-2912
Pacetti, P.; Mambrini, A.; Paolucci, R.; Sanguinetti, F.; Palmieri, B.; Della Seta, R.; Muttini, M.P.; Fiorentini, G.; Cantore, M. 2006: Intra-arterial chemotherapy: a safe treatment for elderly patients with locally advanced breast cancer In Vivo 20(6a): 761-764
Shingai, T.; Furukawa, J.; Azama, T.; Takekuni, K.; Katsumoto, Y.; Yukawa, M.; Nakaguchi, K.; Okajima, S.; Sue, F.; Hashimoto, T.; Yoshihara, W. 2000: A case of locally advanced breast cancer successfully resected after selective intra-arterial chemotherapy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 27(12): 1819-1822
Ashino, Y.; Goto, H.; Oigawa, K.; Yamaguchi, I. 1991: Intra-arterial infusion chemotherapy for locally advanced breast cancer using implantable reservoir connected with catheter inserted in recurrent radial artery Gan to Kagaku Ryoho. Cancer and ChemoTherapy 18(11): 1968-1971
Nicolato, A. 1990: Intra-arterial regional chemotherapy and intensive loco-regional radiotherapy in the treatment of locally advanced cancer of the breast La Radiologia Medica 80(3): 347-351
Morandi, C.; Colopi, S.; Cantore, M.; Molani, L.; Calzona, C.; Reggiani, G.; Amadori, M.; Smerieri, F.; Pellecchi, G. 1996: Intra-arterial chemotherapy in locally advanced or recurrent breast neoplasms La Radiologia Medica 92(1-2): 101-104
Honda, Y.; Kessoku, T.; Kusakabe, A.; Matsuura, T.; Yoshimi, A.; Goto, A.; Yoshida, H.; Sukegawa, A.; Hata, C.; Saito, Y.; Miyashita, Y.; Yashiro, R.; Komori, T.; Arai, S.; Kamata, Y.; Shimizu, T.; Mitsudo, K.; Koizumi, T.; Tohnai, I.; Nakajima, A.; Ichikawa, Y. 2018: Patient Factors Enabling the Decannulation of the Gastrostomy Tube after Superselective Intra-Arterial Chemoradiation Therapy for Locally Advanced Oral Cancer - A Retrospective Study Gan to Kagaku Ryoho. Cancer and ChemoTherapy 45(Suppl. 1): 104-106
Takeuchi, K.; Taniguchi, H.; Miyata, K.; Ueshima, Y.; Okano, S.; Oguro, A.; Sawai, K.; Takahashi, T. 1992: Recurrence and survival rate of advanced gastric cancer after preoperative cisplatin intra-arterial injection therapy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 19(10 Suppl): 1686-1689
Izumi, M.; Iino, Y.; Yokoe, T.; Inoue, T.; Yamada, T.; Kobayashi, I.; Andoh, T.; Yokota, T.; Iijima, T.; Morishita, Y. 1994: Advanced breast cancer with remarkable response to the combination therapy of mitoxantrone (MIT) and medroxyprogesteron acetate (MPA) after failure of anthracycline therapy: a case report Gan to Kagaku Ryoho. Cancer and ChemoTherapy 21(2): 265-268
Voznyĭ, E.K.; Gurov, S.N.; Dobrovol'skaia, N.I. 2001: Certain aspects of neoadjuvant therapy of locally advanced breast cancer Voprosy Onkologii 47(6): 690-694
Voznyĭ, E.K.; Gurov, S.N.; Dobrovol'skaia, N.I. 2001: Certain aspects of neoadjuvant therapy of locally advanced breast cancer Voprosy Onkologii 47(6): 690-694
Manziuk, L.V.; Komov, D.V.; Khaĭlenko, V.A.; Artamonova, E.V.; Mikhina, Z.P.; Ermilova, V.D.; Abashin, S.I. 2001: Combination therapy of patients with locally advanced breast cancer Voprosy Onkologii 47(6): 740-743
Ichikawa, W.; Togo, S.; Osanai, T.; Miyanaga, T.; Sawai, S.; Yamashita, T.; Kawachi, Y.; Nihei, Z.; Hirayama, R.; Mishima, Y. 1994: Clinical study on the effect of intra-arterial injection of mitoxantrone-lipiodol emulsion for hepatocellular carcinoma Gan to Kagaku Ryoho. Cancer and ChemoTherapy 21(13): 2212-2214
Murata, T.; Uda, M.; Nagata, K.; Harima, K.; Nishida, T.; Kawa, S.; Oshima, T.; Tanaka, Y.; Okuda, M.; Seki, Y. 1994: Clinical study of cyclic intra-arterial chemotherapy using mitoxantrone for advanced hepatocellular carcinoma Gan to Kagaku Ryoho. Cancer and ChemoTherapy 21(12): 1991-1996
Swain, S.M.; Lippman, M.E. 1989: Systemic therapy of locally advanced breast cancer: review and guidelines Oncology 3(1): 21-8; Discussion 28-30 34
Karelin, M.I.; Atroshchenko, A.V.; Shkol'nik, M.I.; Leonenkov, R.V.; Belov, A.D.; Kharitonov, M.V. 2008: Combination therapy of localized and locally-advanced renal-cell cancer using preoperative arterial embolization Voprosy Onkologii 54(1): 95-97
Dank, M.; Zergenyi, E.; Domotori, Z.S.; Lahm, E.; Kulka, J. 2003: Primary systemic therapy (PST) of locally advanced breast cancer using Doxorubicin/Docetaxel combination Anticancer Research 23(3c): 2879-2880
Takatsuka, Y.; Yayoi, E.; Kobayashi, T.; Aikawa, T.; Kotsuma, Y. 1992: A prospective randomized study of intra-arterial infusion chemotherapy in the treatment of advanced breast cancer Gan to Kagaku Ryoho. Cancer and ChemoTherapy 19(10 Suppl): 1617-1620