Certain aspects of neoadjuvant therapy of locally advanced breast cancer
Voznyĭ, E.K.; Gurov, S.N.; Dobrovol'skaia, N.I.
Voprosy Onkologii 47(6): 690-694
2001
ISSN/ISBN: 0507-3758 PMID: 11826490 Document Number: 250628
The paper presents the results of a complex investigation of patients with locally-advanced breast cancer who received neoadjuvant chemotherapy or chemoradiation at initial stage. The clinical and pathomorphological effects, nature of neoadjuvant therapy and number of courses were followed up for 5- and 10-year periods. A direct correlation was found between number of courses for chemotherapy-sensitive patients, on the one hand, and greater effect, more intensive medicinal pathomorphism and longer recurrence-free survival, particularly, at later stages, on the other.
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