In vitro activity of a new polyene, SPA-S-843, against yeasts
Rimaroli, C.; Bruzzese, T.
Antimicrobial Agents and ChemoTherapy 42(11): 3012-3013
1998
ISSN/ISBN: 0066-4804 PMID: 9797244 Document Number: 489156
The in vitro activity of a new water-soluble polyene, SPA-S-843, was evaluated against 116 strains of Candida, Cryptococcus, and Saccharomyces spp. and compared with that of amphotericin B. SPA-S-843 demonstrated better inhibitory activity against all of the yeasts examined and better fungicidal activity against Candida albicans, Candida glabrata, Candida krusei, and Candida tropicalis than did amphotericin B.
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