The possibilities of arifon in the combined therapy of unstable stenocardia in persons with arterial hypertension
Iakovlev, V.M.; Sokolov, G.S.
Terapevticheskii Arkhiv 69(6): 53-55
1997
ISSN/ISBN: 0040-3660 PMID: 9297277 Document Number: 474530
The authors studied the effect of arifon on vascular-platelet hemostasis in patients with unstable angina pectoris and hypertension. It was established that arifon addition to standard treatment leads to a decrease of platelet aggregation. A degree of spontaneous aggregation under arifon administration reduced to 30.9%, the rate of spontaneous aggregation decreased to 47.6% versus 13.3 and 24.6%, respectively, in arifon-untreated patients. Arifon promoted reduction of ADP-induced platelet aggregation to 26.9% (without arifon 6.5%); p < 0.01.