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The use of plasmapheresis in the combined treatment of patients with unstable stenocardia

Mal'ginov, S.V.; Zaruba, A.I.; Kutsenko, A.I.; Eliseev, A.O.; Rakhmedov, D.R.; Kukharchuk, V.V.

Terapevticheskii Arkhiv 63(10): 131-133

1991

ISSN/ISBN: 0040-3660
PMID: 1805411
Document Number: 382858
Plasmapheresis (PA) was provided to 82 patients with unstable angina pectoris refractory to drug treatment. PA did not influence blood osmolarity, acid-base equilibrium or blood electrolyte level. The patients manifested a slight rise of hematocrit and a decrease of plasma oncotic pressure. PA gave rise to a significant lowering of blood viscosity, a reduction of blood fibrinogen, total protein, cholesterol and triglycerides. Clinically, there was a marked decline of the frequency of angina pectoris of rest and effort attacks. The doses of antianginal drugs could be reduced. PA brought about a significant rise of the count of rosette-forming cells. The increase of drug sensitivity induced by PA sessions correlated with the clinical efficacy of the treatment. Later on the antianginal effect was attained with far lower drug doses.

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