Spectrophotometric analysis of tetracycline hydrochloride in the presence of thiamine bromide and riboflavin

Efimovskikh, S.V.; Anokhina, T.A.

Antibiotiki i Khimioterapiia 36(8): 18-20

1991


ISSN/ISBN: 0235-2990
PMID: 1755703
Document Number: 4621
Spectrophotometric determination of tetracycline hydrochloride concentrations in the presence of thiamine bromide and riboflavin at a light absorption wave length of 300 nm was shown possible. When the ratio of tetracycline hydrochloride and the total of thiamine bromide and riboflavin (w/w) was at least 10:1 the error of the method was less than 2 per cent. The procedure is useful in quality control of the dosage forms.

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Spectrophotometric analysis of tetracycline hydrochloride in the presence of thiamine bromide and riboflavin