Effect of intravenous polyunsaturated phosphatidyl choline in experimental atherosclerosis
Howard, A.N.; Patelski, J.
Verhandlungen der Deutschen Gesellschaft für Innere Medizin 78: 1245-1248
1972
ISSN/ISBN: 0070-4067 PMID: 4198779 Document Number: 45142
The relationship between the metabolism of phospholipids, glycerides and cholesterol esters in the arterial wall and the development of atherosclerosis has become a subject of considerable interest in recent years. We have shown [1] that in experimental atherosclerosis in rats and in rabbits, there is an increase in lipase and phospholipase activity and a decrease in cholesterol esterase activity in the arterial wall and it is suggested that these might be contributing factors in the production of the arterial lesions.