Synthesis and antibacterial activity of substituted 4-arylaminopyrimido[5,4-c]cinnolines

Nargund, L.V.; Nargund, K.S.

Arzneimittel-Forschung 45(10): 1131-1132

1995


ISSN/ISBN: 0004-4172
PMID: 8595075
Document Number: 447638
A series of 4-arylamino pyrimido[5,4-c]cinnolines was synthesized and evaluated for antibacterial activity by serial 2-fold dilution technique. Several compounds showed significant activity. Amongst them 7-methyl-4-[(p-methyl phenyl) amino] pyrimido [5,4-c] cinnoline (2f) was the most active against Gram positive bacteria.

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