The antioxidizing activity of malonic acid derivatives
Dorovskikh, V.A.; Zrazhevskaia, E.V.; Borodin, E.A.; Borodina, G.P.
Eksperimental'naia i Klinicheskaia Farmakologiia 55(3): 34-37
1992
ISSN/ISBN: 0869-2092 PMID: 1458159 Document Number: 399496
Nine newly synthesized malonic acid derivatives were shown to have antioxidizing activity which makes up from 30 to 60% of the antioxidizing activity of ionol and vitamin E in vitro and does not yield to the activity of the latter substances in vivo. It is suggested that malonic acid derivatives may influence the antioxidizing enzymes--catalase, glucose-6-phosphate dehydrogenase and superoxide dismutase.