Experimental atherosclerosis and its correction with Co-35
Dzhuraev, K.N.; Nasriddinova, N.N.
Biulleten' Eksperimental'noi Biologii i Meditsiny 114(9): 256-257
1992
ISSN/ISBN: 0365-9615 PMID: 1477348 Document Number: 397485
Initial and Co-35-induced parameters of lipid metabolism and hemostasis were studied in rabbits with experimental atherosclerosis. Control atherosclerotic animals were administered cobalt chloride and placebo. The findings demonstrated initially increased levels of cholesterol, lecithin, beta-lipoproteins, lysolecithin, sphingomyelin, cephalin, saturated acids in low levels of phosphatidylserine, polyglycerophosphatide and unsaturated acids. Hemostasis was characterized by hypercoagulation. A course of Co-35 brought about positive shifts in both lipid metabolism and hemostasis. Co-35 is recommended as an effective means against atherosclerosis.