Bacterial endotoxin: molecular relationships between structure and activity
Rietschel, E.T.; Seydel, U.; Zähringer, U.; Schade, U.F.; Brade, L.; Loppnow, H.; Feist, W.; Wang, M.H.; Ulmer, A.J.; Flad, H.D.
Infectious Disease Clinics of North America 5(4): 753-779
1991
ISSN/ISBN: 0891-5520 PMID: 1723739 Document Number: 372581
The significance of endotoxins in bacterial infection and their role as bacterial surface antigens (O antigens) have stimulated investigations into their chemical nature and the mechanisms of their biologic action during the last few decades. This article summarizes some of the recent results and emphasizes structure-activity relationships.