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Effect of nitroglycerin and nicardipine on ICG excretion during halothane anesthesia

Aono, J.; Ueda, W.; Hirakawa, M.

Masui. Japanese Journal of Anesthesiology 40(3): 406-409

1991

ISSN/ISBN: 0021-4892
PMID: 1906552
Document Number: 372580
We evaluated the effect of nitroglycerin and nicardipine on ICG excretion during halothane anesthesia in man. Induced hypotension with nitroglycerin during halothane anesthesia produced a significant prolongation in ICG excretion. No such significant prolongation occurred in the patients who received nicardipine. The results suggest that a reduction in hepatic blood flow during anesthesia may be much less in patients who receive halothane with nicardipine than in those who receive halothane with nitroglycerin.

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